1. What is Cranberry Extract?
MR Natural Cranberry Extract is a kind of standardized herbal extract of Vaccinium macrocarpon L frozen fruit.
Cranberries are a group of evergreen dwarf shrubs or trailing vines in the subgenus Oxycoccus of the genus Vaccinium. In Britain, cranberry may refer to the native species Vaccinium oxycoccos, while in North America, cranberry may refer to Vaccinium macrocarpon. Vaccinium oxycoccos is cultivated in central and northern Europe, while Vaccinium macrocarpon is cultivated throughout the northern United States, Canada and Chile. In some methods of classification, Oxycoccus is regarded as a genus in its own right. They can be found in acidic bogs throughout the cooler regions of the Northern Hemisphere.
2. Source of cranberry.
MR Natural use Cranbery Fruit Origin from USA and Canada.
Place of processing is in Shaanxi province.
3. Basic physical and chemical properties of Cranberry Extract powder
| ANALYSIS | SPECIFICATION |
| Appearance | Violet fine powder |
| Odor | Characteristic |
| Tasted | Characteristic |
| Available spec: | |
| American Cranberry ExtractPart Used:Frozen Cranbery Fruit Origin from U.S.A and CanadaBotanical Name:Vaccinium Macrocarpon L | PACs 15% BL-DMAC methodPACs 30% EP method(Most popular)PACs 10% EP method |
| Chinese cranberry extractPart Used:Fruit Origin from North East Of China | Proanthocyanidins 5%-70% UV Extract Ratio 4:1,10:1 |
| Sieve Analysis | 100% pass 80 mesh |
| Loss on Drying | 5% Max. |
| Ash | 5% Max |
| Extract Solvent | Ethanol & Water |
| Heavy Metal | 10ppm Max |
| Pb | 3ppm Max |
| As | 1ppm Max |
| Hg | 0.1ppm Max |
| Cd | 1ppm Max |
| Residual Solvents | 0.05% Max. |
| Microbiology | |
| Total Plate Count | 10000 cfu/g Max |
| Yeast & Mold | 100 cfu/g Max |
| E.Coli | Negative |
| Salmonella | Negative |
Contaminants of cranberry extract
Pahs,(Benzo(a)anthracene, Benzo(b)fluoranthene, Benzo(a)pyrene, Chrysene
Testing Results of MR Natural Cranberry extract
| PAHs | Benzo(a)anthracene | ND(<1) | ppb(μg/kg) | SPE-HPLC-FLD |
| PAHs | Benzo(b)fluoranthene | 1.1 | ppb(μg/kg) | SPE-HPLC-FLD |
| PAHs | Benzo(a)pyrene | 1.5 | ppb(μg/kg) | SPE-HPLC-FLD |
| PAHs | Chrysene | ND(<1) | ppb(μg/kg) | SPE-HPLC-FLD |
MR Natural Cranberry extract heavy metals test results
| Test Items | Results | Units | Methods | |
| Pb | 0.028 | ppm(mg/kg) | ICP-MS | |
| As | 0.05 | ppm(mg/kg) | ICP-MS | |
| Hg | ND(<0.005) | ppm(mg/kg) | ICP-MS | |
| Cd | ND(<0.005) | ppm(mg/kg) | ICP-MS |
MR Natural Cranberry Extract Microbiological Testing
| Total Plate Count | <300 | cfu/g | CP2015 |
| Mold | 10 | cfu/g | CP2015 |
| Yeast | <20 | cfu/g | CP2015 |
Nutritional Information Of MR Natural Cranberry Extract
| Protein | 2.3 | g/100g | USP |
| Fat | 2.7 | g/100g | USP |
| Carbohydrates | 90.6 | G/100g | USP |
| Energy | 395.9 | Kcal/100g | USP |
4. Manufacturing Flow Chart of Cranberry Extract
Frozen Cranberry Fruit Test→Extracted with water→Separate the impurities from the extract liquid→ Absort PACs in purified extract liquid through big-pores absorbed resin → Wash the resin column by 70% ethanol, and collect the liquid→Reecover the ethanol in the liquid→ Condense→Spray dried→Cranberry extract powder→testing→mix, quantify and pack→testing→store in warehouse.
5. Cranberry Extract Powder benefits
a. Prevent urinary tract infection
The most unique effect of cranberry is that it can effectively prevent urinary tract infections (UTI). 80% to 90% of urinary tract infections are caused by E. coli. Scholars at home and abroad have been studying the mechanism of this function for many years. Various acidic substances in cranberry can increase the acidity of urine in the bladder, and the strong acidic environment formed can kill E. coli in the urethra. In 1998, a research report by Howell AB, a scientist at the State University of New Jersey, et al. confirmed for the first time that the active substance in cranberry that is responsible for inhibiting urinary infections is the concentrated tannins or proanthocyanidins (PACs) isolated from cranberries. Procyanidins are concentrated tannins, mainly oligomers or polymers of epicatechin and epigallocatechin. The content of proanthocyanidins in cranberry is 34.3 mg/100 g. A large number of studies have shown that it has anti-bacterial adhesion properties and can prevent pathogenic bacteria such as Escherichia coli from adhering to the epithelial cells of the urethra and the bladder wall. The pathogenic bacteria flow away with the urine, thereby preventing the occurrence of urinary tract infections.
b. Helicobacter pylori
The proanthocyanidins, ellagic acid, phenolic acid, resveratrol and other substances contained in cranberries have antibacterial effects. Many studies have shown that cranberry can inhibit Helicobacter pylori infection and has a good effect on preventing gastric ulcer, gastric cancer, and duodenal ulcer.
c. anti-oxidation
The flavonoids in cranberry have antioxidant functions in in vivo and in vitro tests, especially flavonols and procyanidins have a preventive effect on atherosclerosis.
d. Prevent cardiovascular disease
Cranberry contains hyperoside, quercetin, myricetone and other flavonol compounds, which together with anthocyanins determine the color of cranberry fruit. Flavonols have strong antioxidant activity, can inhibit the oxidation of low-density lipoprotein-cholesterol, reduce the level of triglycerides in the blood, and help promote the body’s cardiovascular health.
e. Protect the mouth and teeth
Studies have found that the substances isolated and extracted from cranberry juice can decompose the flora in the oral cavity, especially the streptococcus mutans in the saliva that can cause dental caries and dental plaque, thereby protecting the teeth.
f. hypotensive
The low sodium and high potassium properties of cranberry make it have the effect of lowering blood pressure. Studies have found that cranberry juice can promote vascular endothelial cells to produce nitric oxide, relax the blood vessels, thereby lowering blood pressure. This helps explain how bilberries can help promote healthy blood pressure levels. Apostolidis et al
The water-soluble cranberry extracts were fused with oregano, rosemary, and rhodiola as raw materials, and their inhibitory effects on α-glucosidase, pancreatic α-amylase and ACE-1 were determined to evaluate their resistance. Oxidative activity, as well as the effect on diabetes and antihypertensive effect. The results showed that the ability of different components to inhibit α-glucosidase, pancreatic α-amylase and ACE-1 after being combined with cranberry extract was significantly enhanced, indicating that cranberry extract has antioxidant properties, lowering blood pressure and Prevent diabetes.
g. Other health functions
Cranberry also has many other health functions, such as laxative bowel movement, lower cholesterol, prevent heart disease, prevent arteriosclerosis, have antioxidant, anti-tumor, anti-viral functions, protect the liver, and fight ulcers.
6. Dosage of Cranberry Extract Powder
Capsules or tablets containing 120-800 mg of dried cranberry taken once or twice daily(For more info, pls refer: https://www.webmd.com/vitamins/ai/ingredientmono-958/cranberry)
7. Cranberry Extract Powder side effects
It seems safe to consume large amounts of cranberries in cooking, but excessive consumption of juice may cause stomach upset. Eating large amounts of cranberries may increase the risk of kidney stones in susceptible people.
8. Safety of Cranberry Extract Powder
Cranberries and cranberry products are generally safe for most people if consumed in moderation.
However, excessive intake may cause stomach upset and diarrhea, and may increase the risk of kidney stones in susceptible people.
9. Cranberry Extract Powder related researches
- Cranberry or trimethoprim for the prevention of recurrent urinary tract infections? A randomized controlled trial in older women, link: https://academic.oup.com/jac/article/63/2/389/711705?login=true
- Standardised high dose versus low dose cranberry Proanthocyanidin extracts for the prevention of recurrent urinary tract infection in healthy women [PACCANN]: a double blind randomised controlled trial protocol, link: https://bmcurol.biomedcentral.com/articles/10.1186/s12894-018-0342-7
- Cranberry Extract Oral : Uses, Side Effects, Interactions, link: https://www.webmd.com/drugs/2/drug-18297/cranberry-extract-oral/details
- Are Cranberry Pills Good for You? Benefits, Side Effects and Dosage, link: https://www.healthline.com/nutrition/cranberry-pills
- Cranberry Extract – an overview | ScienceDirect Topics, link: https://www.sciencedirect.com/topics/neuroscience/cranberry-extract
10. Cranberry Extract Powder package & Notes for shipping
25kgs/drum, inner by double plastic bags.
N.W./G.W.: 25kgs/28kgs
Drum size: 35cm(diameter)*51cm(height)
Small order is accepted too. Such like 1kg/5kgs/10kgs.
Package for small quantity is by aluminium foil bag and carton box.
For 1-50kg, we suggest shipping by courier, such as DHL, fedex. HS code we use is 2932999099.
For 50-300kgs, we suggest shipping by air. HS code we use is 2932999099/1302199099.
For more than 300kgs, we suggest shipping by sea. HS code we use is 1302199099.
11. Q & A for Cranberry Extract Powder
Q: What is cranberry extract good for?
A: Cranberry has been used for reducing the risk of “bladder infections” (urinary tract infections). It has also been used for decreasing the smell of urine in people who are unable to control urination (incontinent).
Q: Is it OK to take cranberry pills everyday?
A: Dosages of up to 1,500 mg per day are safe for most. Cranberry pills may be worth a try for those who get frequent urinary tract infections or want some extra antioxidant support.
Q: What are the side effects of taking cranberry pills?
A: Common side effects of Cranberry include:
Stomach or abdominal upset.
Diarrhea.
Kidney stones at high doses.
Increased risk of cancer oxalate uroliths in predisposed patients.
Q: Does cranberry extract help UTI?
A: Pure cranberry juice, cranberry extract, or cranberry supplements may help prevent repeated UTIs in women, but the benefit is small. It helps about as much as taking antibiotics to prevent another UTI. Using cranberry products to prevent UTIs may be expensive, and some women complain of the taste.
Q: Does cranberry extract help you lose weight?
A: Added sugar in dried cranberries may not be as helpful in losing weight. Raw and fresh cranberries are naturally low in calories and can be included in weight loss diet. Dried cranberries too can be included in weight loss diet, as far as you eat the organic ones without any adulteration.
Q: Do cranberry pills make you pee red?
A: continued pain or burning when you urinate; vomiting, severe stomach pain; or. signs of a kidney stone–painful or difficult urination, pink or red urine, nausea, vomiting, and waves of sharp pain in your side or back spreading to your lower stomach and groin.
Q: How long do cranberry pills take to work?
A: Although not all women taking the cranberry supplement avoided urinary tract infections (15 out of 80 compared with 30 out of 80), the researchers found a later onset in most cases for those who were using it—18 days as opposed to 8.5 days after surgery.
Q: Do cranberry pills interact with any medications?
A: Cranberry might decrease how quickly the body breaks down atorvastatin (Lipitor). Drinking cranberry juice while taking these medications might increase the effects and side effects of atorvastatin (Lipitor). Avoid drinking large amounts of cranberry juice if you are taking atorvastatin (Lipitor).
12. Supplements containing Cranberry Extract Powder
- AZO Cranberry Tablets, 50 Count
- Cranberry Pills w/ Vitamin C by Nature’s Bounty, Supports Urinary & Immune Health, 4200mg
- Horbaach Cranberry (30,000 mg) + Vitamin C 150 Capsules | Triple Strength Ultimate Potency
- Puritan’s Pride One A Day Cranberry Capsules, 120Count
- Solaray D-Mannose with CranActin Cranberry Extract 1000mg | 60 Count
- ellura 36 mg PAC (90 caps) – Highly Effective Urinary Tract Supplement
- NOW Supplements, Mannose Cranberry, Dual Action Formula*, Clinically Evaluated, Urinary
13. Where you can buy Cranberry Extract Powder?
You can purchase Cranberry Extract Powder from China. MR Natural is a reliable supplier for high quality Cranberry Extract Powder. We supply it to Europe.
For cranberry extract supplements, YOU can buy from online store like Amazon.
14. Other herbal extract for women health
D mannose
Soybean Extract
Black cohosh Extract
Pueraria extract
Red clover extract
